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Copyright ? 2020 Elsevier B.V.
Cell Reports

7x彩票网邀请码The immune composition of the tumor microenvironment influences response and resistance to immunotherapies. While numerous studies have identified somatic correlates of immune infiltration, germline features that associate with immune infiltrates in cancers remain incompletely characterized. We...

Initiation of Ferroptosis by Inhibition of Xc-system or GPX4 Activity
Nature Chemical Biology

Ferroptosis is widely involved in degenerative diseases in various tissues including kidney, liver and brain, and is a targetable vulnerability in multiple primary and therapy-resistant cancers. Accumulation of phospholipid hydroperoxides in cellular membranes is the hallmark and rate-limiting...


Issue 23, December, 2019

Featured Researchers

Headshot of Dr. Andy Mungall
Interviewed by Cindy Kyi, Ph.D.
Last updated: March 12, 2020