CGCI: Cancer Genome Characterization Initiative

7x彩票网邀请码The Cancer Genome Characterization Initiative (CGCI) uses molecular characterization to uncover distinct features of rare cancers. Current projects perform comprehensive molecular cataloging of HIV+ and other rare adult and pediatric cancers. The research community can use CGCI data to gain insights into the underlying mechanisms of these cancers and identify potential therapeutic targets.

Cancer Genome Characterization Initiative Banner. Links to Program Page

News & Publications

Strand split artifact reads (SSAR) mapping and diagrammatic depiction of the proposed mechanism
January 25, 2019

Tissues used in pathology laboratories are typically stored in the form of?formalin-fixed,?paraffin-embedded?(FFPE)?samples. One important consideration in repurposing FFPE material for?next?generation?sequencing?(NGS) analysis is the?sequencing?artifacts that can arise from the significant...

Projects

Burkitt Lymphoma

7x彩票网邀请码The goal of the Burkitt Lymphoma Genome Sequencing Project (BLGSP) is to explore potential genetic changes in patients with that could lead to better prevention, detection, and treatment of this rare and aggressive cancer.

HIV+ Tumor Molecular Characterization Project

The Office of Cancer Genomics (OCG), along with the , initiated the HIV+ Tumor Molecular Characterization Project (HTMCP) to gain insight into the genetic events driving HIV-associated cancers and to determine why certain cancers, but not others, have higher incidences in HIV-positive patients.

Medulloblastoma- Complete

CGCI developed the Medulloblastoma Project to apply newly emerging genomic methods towards the discovery of novel genetic alterations in .?This medulloblastoma study is complete; please refer to the publication.

Non-Hodgkin Lymphoma- Complete

CGCI initiated the Non-Hodgkin Lymphoma Project to elucidate the mutation spectrums of the two most abundant forms of : follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL).?This project is complete, and publications can be found here.?

Last updated: January 15, 2020