OCG Templates and Protocols

The OCG Standard Operating Procedures?(SOPs)?and templates?are guidelines for investigators participating in?OCG programs such as CGCI's?Burkitt Lymphoma Genome Sequencing Project (BLGSP)?and HIV+ Tumor Molecular Characterization Project (HTMCP), the Human Cancer Models Initiative (HCMI),?and Therapeutically Applicable Research to Generate Effective Treatments (TARGET).?Investigators must follow the protocols in the SOPs when contributing samples and data. The sample and data acquisition processes are?explained in comprehensive detail to ensure that all materials and data will be of sufficient quality. Depending on specific involvement during the acquisition process, only a certain number of protocols may apply to each?investigator. Should you require any clarification, please contact?OCG by emailing to ocg@mail.nih.gov.

Burkitt Lymphoma Genome Sequencing Project (BLGSP) Standard Operating Procedures (SOP) Manual

CDE (Common Data Element) Browser User Guide

Experimental Methods for Burkitt Lymphoma Genome Sequencing Project

On this page, researchers can find data generation and data analysis protocols from the following manuscript :

Grande BM, Gerhard DS, Jiang A, et al. Genome-wide discovery of somatic coding and non-coding mutations in pediatric endemic and sporadic Burkitt lymphoma.?Blood. March 2019; 21;133(12):1313-1324. ()

HCMI Case Report Forms (CRFs)

Human Cancer Models Initiative's cancer type-specific CRFs have been developed through collaborations with international clinical experts and the clinical data elements have been standardized through the Cancer Data Standards Registry and Repository (caDSR). Enrollment and Follow-up CRFs are available below for download. The?Enrollment CRF data are collected at the patient index date, which includes initial pathologic diagnosis, sample procurement, or first patient visit. The Follow-up CRF data are collected at least 3 months after enrollment data collection following model establishment.As the tumor types modeled through the HCMI are constantly updated, be sure to check back regularly for additional or updated CRFs. Note: In some cases, it is possible to collect tissues from different tumor sites?(e.g. primary, metastatic, and/or recurrent) from the same patient for model development.?New CRFs capture information about multiple models developed from the same patient?within a single form. The multiple model CRFs are designated with "-multi" within the file name. Versioning is used if there are any subsequent edits to the CRFs.?

HCMI 7x彩票网邀请码able Catalog User Guide

This guide provides users with a resource to effectively navigate the HCMI 7x彩票网邀请码able Catalog.

HCMI 7x彩票网邀请码able Catalog User Guide

HIV+ Tumor Molecular Characterization Project (HTMCP) Standard Operating Procedures (SOP) Manual

Informed Consent Template for Tissue Accrual to Enable Model Development and Distribution

Successful Standard Operating Procedures (SOPs)

7x彩票网邀请码Standard Operating Procedures (SOPs) are written instructions for doing a specific task in a certain way (Source: NCI).? The purpose of an SOP is to guide a novice to carry out a particular task in an accurate and consistent manner.

Download:?PDF iconCharacteristics_of_Successful_SOPs.pdf

TARGET Project Experimental Methods

On this page researchers can find detailed information describing how TARGET data was generated by genomic platform, including protocols for establishing high-quality nucleic acid samples.